Serum Ferritin as predictor of 30day mortality in patients with decompensated chronic liver disease

Background: Serum ferritin is a marker for hepatic neco-inflammation and known 1 year mortality predictor in post-transplant patients. Data on an early mortality predictor in patient of cirrhosis is scare. We investigated whether ferritin can be used as one month mortality predictor in these patients.Methods: 132 patients with decompensated cirrhosis admitted in medical unit III were included and the patients were followed for a period of 30 days. ResultsSerum ferritin levels were significantly different between the survivors and the non-survivors (p < .001) and showed significant correlation with CTP Score (p <.001) and MELD Score (p <.001). Regarding child class and outcome, 22 (22 alive) patients were in class A, 56 (50 alive, 6 died) were in class B and 54 (19 alive, 35 died) were in class C (p <.001). Regarding ferritin level and outcome 76 (76 alive) were having ferritin level <200, 26 (13 alive, 13 died) were having ferritin level between 200-400 and 30 (2 alive, 28 died) were having ferritin level >400 ng/ml (p .001). It was also noted that with increasing ferritin level, CTP class and MELD Score increased. Conclusion: Serum ferritin levels correlate with severity of liver disease and associated with early mortality in patients of decompensated cirrhosis independent of the MELD score