November 4 (Fri.), 15:04–15:44, Room 16 (Kobe International Exhibition Hall No. 2 Building Hall (North) Digital Poster Session)
IP-57_H
Usefulness of Albumin-Bilirubin-based Japan Integrated Staging (ALBI-T) score among Chinese patients with hepatocellular carcinoma
A. W. H. Chan1
Co-authors: A. K. C. Chan2, C. C. N. Chong3, W. Yeo4, P. B. S. Lai3, K.-F. To1, S. L. Chan4
1
Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong
2
Department of Chemical Pathology, The Chinese University of Hong Kong
3
Department of Surgery, The Chinese University of Hong Kong
4
Department of Clinical Oncology, The Chinese University of Hong Kong
Background Japan Integrated Staging(JIS) for hepatocellular carcinoma(HCC) has been extensively studied in hepatitis virus C-endemic Japanese population but seldom evaluated outside Japan, while Albumin-Bilirubin (ALBI)-based JIS(ALBI-T) has never been externally validated. Methods A cohort of 1973 Chinese patients with HCC was employed to evaluate the prognostic performance of JIS and ALBI-T scores by homogeneity likelihood chi-square, Harrell's c-index and corrected Akaike information criterion(AICc). Results The ALBI-T score showed better prognostic performance than the JIS score, which were indicated by homogeneity likelihood chi-squares (ALBI-T 813.57 vs. JIS 781.94), c-indices (ALBI-T 0.74 vs. JIS 0.73) and AICs (ALBI-T 16573.51 vs. JIS 16605.15). Conclusions The ALBI-T score is applicable to Chinese patients to provide good prognostic information.
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