November 4 (Fri.), 10:50–11:30, Room 16 (Kobe International Exhibition Hall No. 2 Building Hall (North) Digital Poster Session)
IP-12_E
Endoscopic resection of gastric carcinoma in the background of adenoma - Predictive factors associated with beyond expanded indication.Outstanding Poster Award
S. H. Park1
Co-authors: K. D. Choi1, S. Lee1, E. J. Gong1, H. K. Na1, J. Y. Ahn1, K. W. Jung1, J. H. Lee1, D. H. Kim1, H. J. Song1, G. H. Lee1, H.-Y. Jung1, J.-H. Kim1
1
Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine
Background/Aims: Clinical outcome after endoscopic resection of gastric carcinoma in the background of adenoma is rarely reported. The aim of this study was to identify predictive factors associated with beyond expanded indication. Methods: We retrospectively analyzed medical records in 342 patients whose final pathology after ESD showed gastric carcinoma in the background of adenoma with described carcinoma component at a single tertiary center between February 2011 and December 2014.Results: Mean patients` age was 64.6±9.4 years and 74.9% were men (n=256). Mean gross tumor size was 2.6±1.7cm. Pathologic result after ESD was confirmed as undifferentiated cancer in 6 patients (1.8%). 16 lesions (4.7%) were SM1 invasion, and 13 lesions (3.8%) were SM2 invasion. 124 lesions (36.3%) were classified as expanded indication and 25 lesions (7.3%) were beyond expanded indication after ESD. In a multivariate analysis gross tumor size>3cm, carcinoma component>30% on pathologic result after ESD and gross ulceration were associated with beyond expanded indication. Conclusions: Gross tumor size, carcinoma component and gross ulceration were the predictive factors associated with beyond expanded indication in patients with carcinoma in the background of adenoma.