Japan Digestive Disease Week 2016
International Poster Session(JDDW)
November 4 (Fri.), 9:30–10:10, Room 16 (Kobe International Exhibition Hall No. 2 Building Hall (North) Digital Poster Session)
IP-5_E
Long-term Outcomes of Peroral Endoscopic Myotomy for Achalasia
- 1
- Digestive Disease Center, Cha Bundang Medical Center
Background: Peroral endoscopic myotomy (POEM) is now accepted as an important treatment option for achalasia. However, long-term clinical outcomes after POEM have been rarely reported.
Methods: The retrospective data were collected from 51 achalasia patients who had a POEM and followed up more than 1 year at our institution. The primary outcome was symptom relief (Eckardt score of < 3). Secondary outcomes were reflux symptoms and lower esophageal sphincter (LES) pressure on manometry.
Results: All patients underwent successful POEM procedure. During a mean follow-up period of 22.5 months (range 12-42 months), 4 patients had repeated POEM. A total of 49 patients (96.0 %) achieved symptom relief. Mean LES pressure also decreased from a mean of 27.8 mmHg to 15.3 mmHg after POEM (p < 0.0001). Thirteen patients (25.5 %) showed gastroesophageal reflux symptoms, but the symptoms did not correlate well with the endoscopic findings and the results of 24-hr pH monitoring.
Conclusion: Relatively long-term outcome of POEM for achalasia are excellent, resulting in symptom relief in almost cases and without serious adverse events.
Methods: The retrospective data were collected from 51 achalasia patients who had a POEM and followed up more than 1 year at our institution. The primary outcome was symptom relief (Eckardt score of < 3). Secondary outcomes were reflux symptoms and lower esophageal sphincter (LES) pressure on manometry.
Results: All patients underwent successful POEM procedure. During a mean follow-up period of 22.5 months (range 12-42 months), 4 patients had repeated POEM. A total of 49 patients (96.0 %) achieved symptom relief. Mean LES pressure also decreased from a mean of 27.8 mmHg to 15.3 mmHg after POEM (p < 0.0001). Thirteen patients (25.5 %) showed gastroesophageal reflux symptoms, but the symptoms did not correlate well with the endoscopic findings and the results of 24-hr pH monitoring.
Conclusion: Relatively long-term outcome of POEM for achalasia are excellent, resulting in symptom relief in almost cases and without serious adverse events.
- Index Term 1: Peroral Endoscopic Myotomy
- Index Term 2: Achalasia