| International Session (Symposium) 1 (JSGE・JGES) |
| Thu. November 1st 9:00 - 12:00 Room 13: Kobe International Conference Center International Conference Room |
| Anorectal cancer with Crohn’ s disease including cancer of anal fistula and the cancer surveillance program in Japan | |||
| Akira Sugita1, Kazutaka Koganei1, Kenji Tatsumi1 | |||
| 1Department of IBD, Yokohama Municipal Citizen's Hospital | |||
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| Purpose : Anorectal cancer including cancer of anal fistula is most common cancer associated with Crohn’s disease(CD) in Japan which is different from western countries. The clinical course and the optimal cancer surveillance program were analyzed in this study. Patents and Methods : 1) Of 1687 CD patients in our hospital, 35 patients had intestinal cancer including 33 with anorectal cancer(cancer of anal fistula:9)(2.0%) . 2) Cancer surveillance by IBD research group, the Ministry of Health, Labor and Welfare of Japan was performed. . The biopsy underwent for the anorectal lesions with more than 10 years duration of anorectal CD. Results: 1) Rectal cancer (24): Median duration of CD was 19 years. The main reason of diagnosis was change of symptoms in 16, cancer surveillance in 4. Cancer stage was stage 0 in 1, I in 4, II in 10, III in 4, IV in 5. Survival rate was 54 % on 42 months after surgery. 2) Cancer of anal fistula(9): Median duration of CD was24 years. The main reason of diagnosis was change of symptoms in 6, incidental diagnosis in 3. Cancer stage was stage II in 3, IV in 2 (4patients: unknown). Survival rate was 67% on 64 months after treatment. 3) Cancer surveillance by IBD research group: Four of enrolled 103 patients were detected anorectal cancer (4%) in our institute. Conclusion: The biopsy for longstanding anal lesion should be performed in the Crohn’s disease patients with change of anal symptoms. The cancer surveillance program by IBD research group are thought to be effective for the detection of anorectal cancer with Crohn’s disease. |
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Index Term 1: Crohn's disease Index Term 2: Anorectal cancer |
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