| International Session（Symposium）4(JSGE・JGES) |
| Fri. November 22nd 9:30 - 12:00 Room 11: Portopia Hotel South Wing Topaz |
| Functional Dyspepsia and Food/FODMAP | |||
| Sutep Gonlachanvit | |||
| Excellence Center on Neurogastroenterology and Motility, Chulalongkorn University | |||
|
|||
|
|||
| Substantial numbers of FD patients develop symptoms after food ingestion. Several gastroduodenal function abnormalities in response to food ingestion have been reported in patients with FD. These include impaired gastric accommodation, delayed gastric emptying and gastroduodenal hypersensitivity to both mechanical and chemical stimulations. Role of specific foods on FD has not been extensively explored. A recent systematic review demonstrated evidences of foods induced dyspeptic symptoms in functional dyspepsia. The foods that induced FD symptoms include fatty foods, gluten containing foods, high FODMAP foods, spicy ingredients, and carbonated drinks. Limited data suggested that some specific foods aggravated FD symptoms differently in different FD subtypes. A study in our center demonstrated that FD patients with epigastrium pain syndrome (EPS) reported the development of abdominal pain or abdominal burning symptoms in response to spicy and sour foods more often than FD with postprandial distress syndrome (PDS). Whereas, fatty foods produced abdominal discomfort/bloating more frequently in FD patients with PDS than EPS. In addition, spicy and sour food produced mainly pain and burning symptoms but fatty foods produced mainly abdominal discomfort and bloating symptoms. The different effects of these 2 common types of Asian foods on FD symptoms suggest that these foods induce FD symptom by different mechanism and support the hypothesis that EPS and PDS are 2 distinct syndromes. High FODMAP diet has been demonstrated to aggravate IBS symptoms in several studies. Some high FODMAP foods such as wheat, milk and some fruits have been reported to associate with FD symptoms. Currently, there are limited data which directly explored the effects of high FODMAP in FD. The explanations that FODMAP can improve FD symptoms include 1) high prevalence of FD and IBS overlap in FGID patients, 2) high FODMAP increases short chain fatty acid which has been reported to affect gastric functions and 3) several high FODMAP foods have gluten protein which may induce FD symptoms. Although, there are limited data on the effects of food on FD symptoms, dietary recommendation for patients with FD should include avoid acute exposure of spicy and sour foods, fatty foods, high FODMAP and gluten containing foods. The amount and eating pattern should also be included in the diet recommendation. Future research studies are needed to establish a better food recommendation for the FD patients. |
|||
| Page Top | |||