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International Session(Symposium)7(JSGS・JSGE・JGES)
Sat. November 23rd   10:00 - 12:00   Room 1: Kobe International Exhibition Hall No.2 Building Hall (North)
IS-S7-2_G
Endoscopic relapse after digestive tract resection in patients with Crohns disease with observations of three years
Shinya Tani1, Satoshi Osawa1, Ken Sugimoto2
1Department of Endoscopic and Photodynamic Medicine, Hamamatsu University School of Medicine, 2First Department of Medicine, Hamamatsu University School of Medicine
Purpose: Endoscopic relapse occurs even if clinical remission has been obtained in patient with Crohns disease in whom intestinal lesions have disappeared after surgery. However, the risk factors for endoscopic relapse are unknown. The factors involved in endoscopic relapse in postoperative patients were examined prospectively.
Methods: Seventeen patients who underwent surgery at our hospital from April 2011 to September 2018 were included. In all patients, intestinal lesions disappeared after surgery. Postoperative maintenance therapy with mesalazine and Elental was administered. Endoscopic examination was performed within six months to one year after the operation. Endoscopic examination was subsequently performed according to the medical condition, and Rutgeert's score of the neoterminal ileum was evaluated.
Results: The median observation period was 40.2 months; 11 patients had endoscopic relapse, and 8 patients had early endoscopic relapse 6 months after surgery. Patients with multiple risk factors such as Montreal Category B3, anal lesions, smoking, history of surgery, and history of biologic administration had significantly more endoscopic relapse than patients with one or less number of risk factor.
Conclusion: Postoperative endoscopic relapses peaked at 6 months after surgery, and 6 months after surgery was considered to be important. Patients with multiple risk factors had a high risk of endoscopic relapse
Index Term 1: Crohn's disease
Index Term 2: postoperative relapse
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