| International Session（Workshop）1(JGES・JSGE・JSGS・JSGCS) |
| Sat. November 23rd 9:30 - 12:00 Room 11: Portopia Hotel South Wing Topaz |
| Probe-based confocal laser endomicroscopy for the in vivo diagnosis of pancreatic ductal structures | |||
| Kazunori Nakaoka1, Senju Hashimoto1, Kentaro Yoshioka1 | |||
| 1Department of Liver, Biliary Tract and Pancreas Diseases, Fujita Health University | |||
|
|||
|
|||
| 【Background and Aims】 The image-based diagnosis of pancreatic disease can be difficult and requires pathological evaluation. Probe-based confocal laser endomicroscopy (pCLE) enables real-time pathological evaluations in vivo and may improve diagnostic abilities. This study aimed to evaluate the feasibility and utility of pCLE for diagnosing pancreatic diseases. 【Methods】Thirty patients who underwent endoscopic retrograde cholangiopancreatography (ERCP) with pCLE for the evaluation of indeterminate pancreatic diseases were included in this study. 【Results】 Among the 30 patients, 12, 10, 4, and 4 received definitive diagnoses of pancreatic ductal adenocarcinoma (PC), main duct intrapapillary mucinous neoplasm (MD-IPMN), autoimmune pancreatitis and chronic pancreatitis, respectively. The diagnostic accuracies of pCLE for PC and pancreatitis (96.7% and 93.3%, respectively) were higher than those of cytology (76.7% and 63.3%, P = 0.0227 and P = 0.0012, respectively). The sensitivity of pCLE for PC was higher (91.7%) than that of cytology (41.7%) (P = 0.0304). Moreover, the specificity of pCLE for pancreatitis was higher (90.9%) than that of cytology (50%) (P = 0.0029). However, the diagnostic accuracies of pCLE and cytology for MD-IPMN did not differ (96.7% and 86.7%, respectively). 【Conclusions】We conclude that pCLE is more effective than cytology for the diagnosis of PC and should be performed during ERCP. |
|||
|
Index Term 1: pCLE Index Term 2: cytology |
|||
| Page Top | |||