International Session（Symposium）3(JSGE・JGES・JSGS・JSGCS)
Thu. November 5th   14:00 - 17:00   Room 11: Portopia Hotel South Wing Topaz
IS-S3-2_G
 The Time Trend of IBD Hospitalization Burden in China
Minhu Chen
Division of Gastroenterology and Hepatology, The First Affiliated Hospital, Sun Yat-sen University
The prevalence of Inflammatory Bowel Disease (IBD) is rising dramatically in the industrialized countries leaving huge burden on the health service system. In the last decade, the number of Chinese IBD patients was increasing evidently, whereas, the responding epidemiological analysis is lacking. In order to reveal the IBD burden in China, we conducted the analysis IBD inpatients’ data from 2013 to 2018. Population based hospitalization rate was calculated by extrapolating the number of patients recorded in the database to all the tertiary centers as a country level. The percentage of obstruction, penetration and surgical rates were calculated as burden of IBD related conditions. The annual hospital charges and length of stay per patient were also generated in quantification of economic hospitalization burden. Poisson regression analysis was applied to analysis the time trends of the hospitalization rate and chi-square trend line test used for analysis of time trends of proportion of complications and surgery. Annual Percentage of Change (APC) was calculated by Log-linear model.
The hospitalization rate of CD rose from 2.20 (95% Confidential Interval [CI]: 2.17-2.22) to 3.62 (95%CI: 3.59-3.65) per 100,000 inhabitants (P<0.0001) with an APC of 11.27% and that of UC increased from 6.24 (95%CI: 6.20-6.28) to 8.29 (95%CI: 8.23-8.33) per 100,000 inhabitants (P<0.0001) with an APC of 5.90% from 2013 to 2018. 0-19 age group in CD demonstrated an APC in hospitalization rate of 17.55% and APC for 0-19 age group in UC was 9.97%, both appeared as the highest APC in all age groups. The proportion of bowel complications in CD patients demonstrated none significant change during the study period, but the surgical rate decreased significantly from 7.96 (95%CI: 7.29-8.63)% to 5.56 (95%CI: 5.11-6.00)% in CD (P<0.001) and from 3.54 (95%CI: 3.26-3.82)% to 2.52 (95%CI: 2.32-2.72)% in UC (P<0.001). The length of stay in hospital decreased by 13 (IQR:15) days to 10 (IQR:11) days in CD and 11 (IQR:12) days to 10 (IQR:10) days in UC during this 6-year period.
In conclusion, the population based hospitalization rate of IBD was rising from 2013 to 2018 in mainland China. Little change observed in complication rates. Surgical rates and the length of hospitalization were dropping at the meantime.
Index Term 1: IBD
Index Term 2: Hospitalization burden
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