| International Session（Symposium）6(JSGE・JGES・JSGS・JSGCS) |
| Fri. November 6th 9:00 - 12:00 Room 11: Portopia Hotel South Wing Topaz |
| Surgical strategy for locally advanced pancreatic cancer in the era of multidisciplinary treatment | |||
| Tsutomu Fujii1, Isaku Yoshioka1, Kazuto Shibuya1 | |||
| 1Department of Surgery and Science, Faculty of Medicine, Academic Assembly, University of Toyama | |||
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| In pancreatic cancer, which is an incurable disease, improved results have begun to be reported due to the advancement of multidisciplinary treatment, including state-of-the-art chemotherapy regimens and improvements in perioperative procedures and management. In the treatment of unresectable (UR) pancreatic cancer, the most innovative recent change is the introduction of FOLFIRINOX and nab-paclitaxel as an effective protocol. By multidisciplinary treatment using them, there are increasing cases in which resection is possible in pancreatic cancer which was unresectable at the time of initial diagnosis. This additional surgical resection is called “Adjuvant surgery” or “Conversion Surgery”, implying strategy-conversion. There is still no clear evidence on the validity and usefulness of this option; however, good prognosis has been reported in locally advanced UR (UR-LA) pancreatic cancer patients little by little. However, a multidisciplinary treatment including regimen, duration of treatment, and timing of surgery require further study as well in UR-LA pancreatic cancer. In addition, surgery for UR-LA pancreatic cancer requires advanced techniques such as portal vein and arterial resection. In conversion surgery for metastatic (UR-M) pancreatic cancer, a thorough verification will be required in the future. I will review previous reports, especially about conversion surgery for initially unresectable locally advanced pancreatic cancer following multidisciplinary treatment, and state the experience including combined radiotherapy and surgical results in our institution. |
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Index Term 1: Locally advanced pancreatic cancer Index Term 2: Conversion surgery |
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