Japan Digestive Disease Week 2021
International Poster Session 4 (JDDW)
November 5, 10:10–10:50, Room 16 (Kobe International Exhibition Hall No.3 Building Digital Poster Venue)
IP-20_S
Inferior Early Liver Transplantation Outcomes during COVID-19 pandemic in the United States Young Award
- 1
- Westchester Medical Center, New York Medical College
Introduction: COVID-19 has been pandemic in 2020. This pandemic impacts liver transplantations (LT) in the United States. The aim of this study was to analyze the effect of COVID-19 pandemic in LT.
Methods: World Health Organization declared a pandemic on March 11th in 2020. We analyzed data from the United Network for Organ Sharing (UNOS) between 2019-2020. We defined as pre-COVID era between March 11thand September 11th in 2019 and COVID era between March 11th and September 11 in 2020. We included the patients age above 18 years old and performed propensity matching and compared the outcomes during the study periods.
Results: 8,384 liver transplants were performed during the study periods. Living donor LT were 411 (4.9%) and no difference during this period. Comparing to pre-COVID era, median recipient age, ratio of recipient gender and median BMI were same (p=NS). Median MELD at transplant was lower in COVID era (25 vs 26, p<0.01) For donor, donor age, ratio of gender and median BMI were same (p=NS), but donor risk index was significantly higher in COVID era (1.73 vs 1.63, p<0.01). After propensity matching, 90-day graft survival was significantly inferior in COVID era (95.1 vs 94.6%, p<0.001).
Conclusions: In COVID era, outcome was significantly inferior to pre-COVID era. Careful postoperative management is mandatory in COVID era.
Methods: World Health Organization declared a pandemic on March 11th in 2020. We analyzed data from the United Network for Organ Sharing (UNOS) between 2019-2020. We defined as pre-COVID era between March 11thand September 11th in 2019 and COVID era between March 11th and September 11 in 2020. We included the patients age above 18 years old and performed propensity matching and compared the outcomes during the study periods.
Results: 8,384 liver transplants were performed during the study periods. Living donor LT were 411 (4.9%) and no difference during this period. Comparing to pre-COVID era, median recipient age, ratio of recipient gender and median BMI were same (p=NS). Median MELD at transplant was lower in COVID era (25 vs 26, p<0.01) For donor, donor age, ratio of gender and median BMI were same (p=NS), but donor risk index was significantly higher in COVID era (1.73 vs 1.63, p<0.01). After propensity matching, 90-day graft survival was significantly inferior in COVID era (95.1 vs 94.6%, p<0.001).
Conclusions: In COVID era, outcome was significantly inferior to pre-COVID era. Careful postoperative management is mandatory in COVID era.
- Index Term 1: COVID-19
- Index Term 2: Liver transplant