Japan Digestive Disease Week 2021
International Poster Session 4 (JDDW)
November 5, 10:10–10:50, Room 16 (Kobe International Exhibition Hall No.3 Building Digital Poster Venue)
IP-18_G
Laparoscopic Surgery is the third, but could be most frequently employed for HCC in sustained virological response (SVR) era.
- 1
- Department of Gastroenterology, Yamanashi Prefectural Central Hospital
- 2
- Department of Internal Medicine, Teikyo University Chiba Medical Center
- 3
- Department of Surgery, Yamanashi Prefecutural Central Hospital
- 4
- The University of Tokyo
AIM: Oral preparation of anti HCV drug completely changed the paradigm of Hepatology. In this communication, we addressed the issue comfortable any drastic change, could be needed for the treatment of HCC in SVR era.
METHODS: We enrolled 612 patients who achieved SVR after DAA between 2013 and 2020. The patient visited the outpatient clinic on a regular basis and was prospectively observed for develop of HCC. We assessed the utility of these major interventions in real world settings.
RESULTS: HCC developed in 48 of 612 (7.8%) patients. The treatment options for HCC were 7:15:16:10 cases of open: laparoscopic: RFA: others, respectively. The 1-, 3-, and 5-year recurrence-free survival rates were 85%, 62%, and 62% for hepatectomy and 63%, 47%, and 28% for RFA, respectively, which were significantly better in the hepatectomy group (p < 0.05). The overall survival rates at 1, 3 and 5 years were 100%, 100% and 83% for hepatectomy and 93%, 83% and 80% for RFA, respectively, showing no significant difference. The most important result was that liver function improved after SVR was achieved, which was advantageous for both treatments.
CONCLUSION: In real world setting, especially in SVR era, laparoscopic surgery could be the third but could be the most preferred of golden of treatment.
METHODS: We enrolled 612 patients who achieved SVR after DAA between 2013 and 2020. The patient visited the outpatient clinic on a regular basis and was prospectively observed for develop of HCC. We assessed the utility of these major interventions in real world settings.
RESULTS: HCC developed in 48 of 612 (7.8%) patients. The treatment options for HCC were 7:15:16:10 cases of open: laparoscopic: RFA: others, respectively. The 1-, 3-, and 5-year recurrence-free survival rates were 85%, 62%, and 62% for hepatectomy and 63%, 47%, and 28% for RFA, respectively, which were significantly better in the hepatectomy group (p < 0.05). The overall survival rates at 1, 3 and 5 years were 100%, 100% and 83% for hepatectomy and 93%, 83% and 80% for RFA, respectively, showing no significant difference. The most important result was that liver function improved after SVR was achieved, which was advantageous for both treatments.
CONCLUSION: In real world setting, especially in SVR era, laparoscopic surgery could be the third but could be the most preferred of golden of treatment.
- Index Term 1: HCC
- Index Term 2: Treatment