Japan Digestive Disease Week 2021
International Session (Workshop)3 (JSH, JSGE, JSGCS)
November 5, 14:30–17:00, Room 8 (Portopia Hotel Main Building Kairaku 1+2)
IS-W3-2_G
Usefulness of shear-wave velocity for the prediction of liver cirrhosis and esophageal varices
- 1
- Second Department of Internal Medicine, Faculty of Medical Sciences, University of Fukui
[Background]
Shear-wave ultrasound elastography (SWE) has been expected as a non-invasive diagnostic method in patients with chronic liver disease (CLD). In this study, we investigated the utility of shear-wave velocity (Vs) for the prediction of liver cirrhosis and esophageal varices.
[Methods]
A total of 104 patients with CLD who underwent SWE between April 2017 and March 2019 were included. Vs values were measured and compared with liver biopsy findings obtained on the same day. The relationship between Vs values and the presence of esophageal varices in 58 patients who underwent esophagogastroduodenoscopy (EGD) within 1 year before and after SWE was also evaluated.
[Results]
Among the 104 patients, 9/23/33/22/17 were histologically diagnosed with F0/F1/F2/F3/F4 CLD, in accordance with the new Inuyama classification. The median Vs values were 1.28/1.17/1.44/1.82/2.12 m/s for patients with F0/F1/F2/F3/F4 CLD. For F4 detection, the area under the receiver-operating characteristic curve (AUC) was 0.903 and sensitivity/specificity were 85.7/85.9%. Esophageal varices were found in 13 patients among the 58 who underwent EGD. Vs values were significantly high in these 13 patients (2.20 vs. 1.47 m/s, P＜0.01), indicating the predictive ability for esophageal varices (AUC 0.871).
[Conclusion]
In patients with CLD, the Vs value of SWE may be useful to stratify the degree of hepatic fibrosis. Moreover, it may help to predict the presence of esophageal varices.
Shear-wave ultrasound elastography (SWE) has been expected as a non-invasive diagnostic method in patients with chronic liver disease (CLD). In this study, we investigated the utility of shear-wave velocity (Vs) for the prediction of liver cirrhosis and esophageal varices.
[Methods]
A total of 104 patients with CLD who underwent SWE between April 2017 and March 2019 were included. Vs values were measured and compared with liver biopsy findings obtained on the same day. The relationship between Vs values and the presence of esophageal varices in 58 patients who underwent esophagogastroduodenoscopy (EGD) within 1 year before and after SWE was also evaluated.
[Results]
Among the 104 patients, 9/23/33/22/17 were histologically diagnosed with F0/F1/F2/F3/F4 CLD, in accordance with the new Inuyama classification. The median Vs values were 1.28/1.17/1.44/1.82/2.12 m/s for patients with F0/F1/F2/F3/F4 CLD. For F4 detection, the area under the receiver-operating characteristic curve (AUC) was 0.903 and sensitivity/specificity were 85.7/85.9%. Esophageal varices were found in 13 patients among the 58 who underwent EGD. Vs values were significantly high in these 13 patients (2.20 vs. 1.47 m/s, P＜0.01), indicating the predictive ability for esophageal varices (AUC 0.871).
[Conclusion]
In patients with CLD, the Vs value of SWE may be useful to stratify the degree of hepatic fibrosis. Moreover, it may help to predict the presence of esophageal varices.
- Index Term 1: SWE
- Index Term 2: CLD