Japan Digestive Disease Week 2021
International Session (Panel Discussion)3 (JGES, JSGE)
November 6, 14:30–17:00, Room 11 (Portopia Hotel South Wing Topaz)
IS-PD3-6_E
ULCERATIONS AT THE SITE OF SMALL INTESTINAL STRICTURES DUE TO CROHN’S DISEASE AFFECTS OUTCOME OF ENDOSCOPIC BALLOON DILATION Young Award
- 1
- Division of Gastroenterology, Department of Medicine, Jichi Medical University
Background: Endoscopic balloon dilation (EBD) is useful for the treatment of small-intestinal strictures due to Crohn’s disease (CD). However, it is unclear whether mucosal healing affects the course of the stricture after EBD. This study aimed to evaluate precise diameter improvement at scheduled EBD depending on the presence of ulcers at small intestinal strictures in patients with CD.
Methods: We retrospectively analyzed data from 39 patients with CD who underwent two sessions of scheduled EBD for de novo small intestinal strictures, between 2016 and 2020. Stricture diameter was measured with a calibrated small- caliber- tip transparent (CAST) hood. The patients were categorized into 4 groups: no ulceration at both sessions (NU; n=18), ulcer healed (UH; n=6), ulcer remaining (UR; n=12), and ulcer developed (UD; n=3). The minimum diameter of strictures was analyzed separately for the groups using the paired t-test. The diameters of improved and unrecognized strictures in the second session were calculated as 12 mm.
Results: A difference in minimum diameter was observed in the NU (+1.72 mm, p=0.04) and UH groups (+1.08 mm, p=0.21). In contrast, strictures did not improve in the UR and UD groups (−0.33 mm, p=0.31 / -0.33 mm, p=0.45).
Conclusion: Mucosal healing of strictures facilitated the efficacy of EBD in patients with small intestinal strictures due to Crohn’s disease.
Methods: We retrospectively analyzed data from 39 patients with CD who underwent two sessions of scheduled EBD for de novo small intestinal strictures, between 2016 and 2020. Stricture diameter was measured with a calibrated small- caliber- tip transparent (CAST) hood. The patients were categorized into 4 groups: no ulceration at both sessions (NU; n=18), ulcer healed (UH; n=6), ulcer remaining (UR; n=12), and ulcer developed (UD; n=3). The minimum diameter of strictures was analyzed separately for the groups using the paired t-test. The diameters of improved and unrecognized strictures in the second session were calculated as 12 mm.
Results: A difference in minimum diameter was observed in the NU (+1.72 mm, p=0.04) and UH groups (+1.08 mm, p=0.21). In contrast, strictures did not improve in the UR and UD groups (−0.33 mm, p=0.31 / -0.33 mm, p=0.45).
Conclusion: Mucosal healing of strictures facilitated the efficacy of EBD in patients with small intestinal strictures due to Crohn’s disease.
- Index Term 1: endoscopic balloon dilation
- Index Term 2: Crohn's disease