International Poster Session 5 (JDDW)
November 5, 14:00–14:48, Room 16 (Kobe International Exhibition Hall No.3 Building Digital Poster Venue)
IP-24_G

Protein intake after the initiation of chemotherapy is an independent prognostic factor for overall survival in patients with unresectable pancreatic cancer: A prospective cohort study.

Yoko Hasegawa1
Co-authors: Hideaki Ijichi1,2, Kei Saito2, Kazunaga Ishigaki2, Maki Takami1, Rie Sekine1, Satomi Usami3, Yousuke Nakai2,4, Kazuhiko Koike2, Naoto Kubota1,5
1
Clinical Nutrition Center, The University of Tokyo Hospital
2
Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo
3
Graduate School of Education, The University of Tokyo
4
Department of Endoscopy and Endoscopic Surgery, The University of Tokyo Hospital
5
Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, The University of Tokyo
Background & Aims: This aim was to investigate the nutritional status and longitudinal dietary intake during the course of chemotherapy, and their relationships with the survival in patients with unresectable pancreatic cancer.
Methods: A prospective cohort study was conducted in 38 patients with unresectable pancreatic cancer receiving chemotherapy between January 2018 and November 2019. Subjective global assessment was used to assess the nutritional status, and the dietary intake was assessed monthly, for up to 12 months, using a brief self-administered diet history questionnaire.
Results: Daily protein intake during one month after the initiation of chemotherapy was significantly higher in the survivor group than in the deceased group. Multivariate Cox regression analysis identified protein intake <1.1 g/kg/day as an independent poor prognostic factor (hazard ratio: 9.03, 95%CI: 1.45-56.32, p=0.018).
Conclusions: Insufficient protein intake was identified as an independent poor prognostic factor in patients with unresectable pancreatic cancer receiving chemotherapy.
Page Top