Japan Digestive Disease Week 2022
International Poster Session11 (JDDW)
October 28, 15:12–15:44, Room 15 (Marine Messe Fukuoka Arena Digital Poster Session)
IP-51_G
Usefulness of MRI diffusion-weighted imaging for surveillance of pancreatic malignancies in patients with low-risk branch-duct intraductal papillary mucinous neoplasms
- 1
- 2nd Department of Internal Medicine, University of Fukui
Background and Aim：MRI plays an important role in surveillance of pancreatic malignancies of IPMNs. Recently, the efficacy of contrast-free MRI imaging protocols in diagnosing pancreatic ductal adenocarcinoma (PDAC) has been reported. The aim of this study is to evaluate the diagnostic accuracy of DWI on the detection of pancreatic malignancies in the patients with low-risk BD-IPMN.
Methods: A total of 111 patients with BD-IPMN without worrisome features or high-risk stigma were retrospectively investigated. Patients underwent routine MRI every 6-24 months with additional CT scan or EUS. We evaluate MRI findings and analyzed the utility of DWI in diagnosing pancreatic malignancies.
Results: The median of initial cyst diameter was 14.7mm. Nine patients developed pancreatic cancer during follow-up (median 61 months), including 5 IPMN-derived cancers, 3 concomitant PDAC, and unclassifiable. The 5- and 8-year cumulative incidence rates of pancreatic cancer were 3.9 and 10.2%, respectively. Hyperintense of DWI was found in 10 cases, and the frequency of hyperintense in pancreatic cancer was significantly higher than that in benign IPMN (P<0.001). Sensitivity, specificity, accuracy of DWI for detecting pancreatic cancer were 0.778, 0.97, and 0.94, respectively.
Conclusion: Continuous surveillance is required even for low-risk BD-IPMN, and DWI findings may be useful in detecting pancreatic malignancies.
Methods: A total of 111 patients with BD-IPMN without worrisome features or high-risk stigma were retrospectively investigated. Patients underwent routine MRI every 6-24 months with additional CT scan or EUS. We evaluate MRI findings and analyzed the utility of DWI in diagnosing pancreatic malignancies.
Results: The median of initial cyst diameter was 14.7mm. Nine patients developed pancreatic cancer during follow-up (median 61 months), including 5 IPMN-derived cancers, 3 concomitant PDAC, and unclassifiable. The 5- and 8-year cumulative incidence rates of pancreatic cancer were 3.9 and 10.2%, respectively. Hyperintense of DWI was found in 10 cases, and the frequency of hyperintense in pancreatic cancer was significantly higher than that in benign IPMN (P<0.001). Sensitivity, specificity, accuracy of DWI for detecting pancreatic cancer were 0.778, 0.97, and 0.94, respectively.
Conclusion: Continuous surveillance is required even for low-risk BD-IPMN, and DWI findings may be useful in detecting pancreatic malignancies.
- Index Term 1: IPMN
- Index Term 2: MRI