| [Aims] We aimed to evaluate whether patients with non-esophageal eosinophilic gastrointestinal diseases (non-EoE EGIDs) had mental disorders similar to that in patients with disorders of gut-brain interaction (DGBI). [Methods] We enrolled patients with non-EoE EGIDs and DGBI, and compared the data of the following questionnaires: hospital anxiety and depression scale (HADS), and SF-8 including mental component score (MCS)-8 to evaluate health-related quality of life. [Results] We evaluated 21 and 26 patients with non-EoE EGIDs and DGBI, respectively. The numbers of patients with each subtype of non-EoE EGIDs were 6, 12, 1, and 11 with eosinophilic gastritis, duodenitis, jejunitis, and colitis, respectively. Anxiety score was not significantly different between patients with non-EoE EGIDs and in those with DGBI (7.0 [5.0, 9.0] vs. 7.0 [5.0, 9.8]). These results demonstrate that patients with non-EoE EGIDs had anxiety equivalent to that of those with DGBI. Depression score in the non-EoE EGID group tended to be lower than that in the DGBI group; however, the difference was not statistically significant (4.0 [3.0, 7.0] vs. 6.0 [3.3, 10.0]). In patients with non-EoE EGIDs, the anxiety score had a significant inverse association with MCS-8 score (p < 0.01, r = -0.598). [Conclusions] Patients with non-EoE EGIDs had anxiety equivalent to that of patients with DGBI. |
