| International Session（Workshop）2(JGES・JSGE・JSH) |
| Fri. November 1st 9:00 - 12:00 Room 11: Portopia Hotel South Wing Topaz |
| Short-term effect of EOI foam sclerotherapy for esophageal varices | |||
| Hidemi Unozawa1, Takayuki Kondo1, Naoya Kato1 | |||
| 1Chiba University Hospital, Department of Gastroenterology | |||
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| Background/Aims: Polidocanol foam sclerotherapy is commonly used as a treatment for varicose veins. However, intravascular administration of polidocanol is not permitted in esophageal varices sclerotherapy (EIS) in Japan; only ethanolamine oleate with iopamidol (EOI) is allowed for intravascular administration. In addition, it is difficult to make stable EOI foam for conventional foam preparation methods. However, a new foam preparation method makes it possible to create stable EOI foam. Therefore, this study aimed to clarify the short-term therapeutic effect of EOI foam sclerotherapy for esophageal varices. Methods: This study included 24 patients who underwent EOI foam sclerotherapy between Jan and Nov 2023 and confirmed the treatment effect by endoscopy six months later, and 105 patients who underwent conventional EIS with 5% EOI were used as a control group. Results: There was no significant difference in the number of treatment sessions until the varices disappeared between the two groups. The total amount of EOI used was significantly lower in the foam sclerotherapy group (14.5 ml) than in conventional sclerotherapy (21.1 ml, P<0.01). The recurrence of varices was significantly lower in foam sclerotherapy (8.3%) than in conventional sclerotherapy (28.6%, P=0.04). Conclusion: EOI foam sclerotherapy can reduce the amount of EOI used compared to conventional EIS and could be the first treatment option for esophageal varices. |
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Index Term 1: foam sclerotherapy Index Term 2: esophageal varices |
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