| Strategic International Session4（S）(JSGE) |
| Sat. November 2nd 9:00 - 11:30 Room 11: Portopia Hotel South Wing Topaz |
| Pancreas Cancer Prevention: Genetics, Screening and Interception | |||
| Marcia Cruz-Correa1,2,3 | |||
| 1University of Puerto Rico Medical Sciences Campus, 2Isaac Gonzalez Martinez Oncologic Hospital, 3Johns Hopkins University School of Medicine | |||
|
|||
|
|||
| Pancreas cancer continues to account for a significant burden of cancer morbidity and mortality. Current risk factors associated with the development of pancreas cancer include hereditary cancer syndromes such as Lynch Syndrome, Hereditary Breast and Ovarian Cancer Risk and mutation in other key genes that account for approximately 10% of all pancreas cancer cases. Other important risk factors such as tobacco, alcohol, diabetes mellitus or chronic pancreatitis continue to account for a significant percentage of the burden of pancreas cancer. Endoscopic methods for screening individuals with hereditary cancer have demonstrated improved outcomes with earlier diagnosis and decreased mortality. Additional strategies such as molecularly based testing including novel ct-DNA tests are evolving and may help identify those with early pancreas cancer. Interception tools such as vaccines are also being evaluated to potential prevent pancreas cancer among high risk populations. |
|||
|
Index Term 1: Pancreas Cancer screening Index Term 2: Circulating tumor DNA |
|||
| Page Top | |||