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Featured Session 1 (JGES,JSGE,JSGS)
Fri. November 1st   9:00 - 11:00   Room 1: Kobe International Exhibition Hall No.2 Building Hall (North)
JGES_FS1-9_E
EUS-guided antegrade stenting using 22G needle combined with closure of the puncture route using self-assembling peptide solution for minimally invasive endoscopic therapy
Hirotsugu Maruyama1, Kojiro Tanoue1, Yasuhiro Fujiwara1
1Department of Gastroenterology, Graduate School of Medicine, Osaka Metropolitan University
[Aim]
Endoscopic ultrasound-guided hepaticogastrostomy (EUS-HGS) combined with EUS-guided antegrade stenting (EUS-AS) has been reported to minimize bile leakage and prolong patency. However, problems are use of two stents and the risk of bile leakage due to the expansion operation during EUS-HGS. We report EUS-AS using a 22G needle combined with closure of the puncture route using self-assembling peptide solution for minimally invasive endoscopic therapy.
[Methods]
We performed EUS-AS using a 22G needle combined with closure of the puncture route using self-assembling peptide solution in 8 consecutive patients. We applied the self-assembling peptide solution using a double lumen cannula after performing EUS-AS.
[Results]
EUS-AS was performed using a laser-cut uncovered metallic stent and was placed across the ampulla of Vater in 4 patients and the anastomosis in 4. Five ml of self-assembling peptide solution could be simply applied in all patients. Technical and clinical success rates were 100% and 75%, respectively. The expansion operations were applied only to the gastric wall in 4 patients. Adverse events such as bile peritonitis or stent dysfunction did not occur during follow-up (median 126 days, interquartile range 72.5 - 195.5 days). No pancreatitis developed, and elevated pancreatic enzymes were in one patient.
[Conclusion]
This method is simple and appears to effectively avoid adverse events associated without EUS-HGS.
Index Term 1: EUS-HGS
Index Term 2: EUS-AS
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