| Featured Session 2 (JGES,JSGE,JSGS) |
| Fri. November 1st 14:40 - 17:00 Room 1: Kobe International Exhibition Hall No.2 Building Hall (North) |
| Gel immersion endoscopic submucosal dissection using a scissor-type knife for superficial non-ampullary duodenal epithelial tumors | |||
| Osamu Dohi1, Naoto Iwai1, Naohisa Yoshida1 | |||
| 1Department of Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine | |||
|
|||
|
|||
| Backgrounds: This study aimed to compare the outcomes of conventional endoscopic submucosal dissection (C-ESD) and gel immersion ESD (GI-ESD) for superficial non-ampullary duodenal epithelial tumor (SNADET). Methods: Patients with SNADETs who underwent C-ESD and GI-ESD between 2016 and 2023 were enrolled. The study outcomes included the en bloc resection, resection time, and adverse events. In C-ESD, we used a scissor-type knife under CO2 insufflation. While, GI-ESD was performed using a scissor-type knife with immersion of gel solution. Results: A total of 109 C-ESD and 57 GI-ESD were analyzed in this study. The rates of en bloc resection and curative resection were 100% vs. 100% and 95.4% vs. 93.0% in the C-ESD and GI-ESD, respectively, with no significant difference. There was also no significant difference of mean resection time in the C-ESD and GI-ESD (64.7 vs. 62.0 min, respectively). The rate of muscle layer exposure was significantly higher in the C-ESD than in the GI-ESD (18.3% vs. 5.3%, respectively, P = 0.021). Moreover, there was 6.9% and 3.5% of major adverse events in the C-ESD and GI-ESD, respectively. Conclusions: GI-ESD for SNADETs are acceptable in terms of the high rate of en bloc and R0 resection with a low rate of adverse events. Gel immersion had several advantages of clear viewing, buoyage effect of mucosa, and stabilization of ESD procedure. |
|||
|
Index Term 1: superficial non-ampullary duodenal epithelial tumor Index Term 2: endoscopic submucosal dissection |
|||
| Page Top | |||