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International Session(Panel Discussion)2(JGES・JSGE・JSGS)
Sat. November 2nd   14:00 - 17:00   Room 9: Portopia Hotel Main Building Kairaku 3
IS-PD2-10_G
Evaluation and clinical significance of population-attributable risk percent in the management of colonic diverticular bleeding
Kyoko Oka1, Naoki Ishii1
1Department of Gastroenterology, Tokyo Shinagawa Hospital
[Objectives] The population-attributable risk percent (PAR%) is the percent of outcomes that could be avoidable if exposures were removed from the population. Recently, the PAR% was used for the reevaluation of gastric cancer screening (Clin Transl Gastroenterol. 2022; 13: e00530). This study aimed to estimate the PAR% of recurrent bleeding in the management of colonic diverticular bleeding (CDB).
[Methods] We used the papers published from the CODE BLUE-J Study performed by Nagata N, et al. Although misclassification of data could lead to the misestimation of risks or treatment effects (N Engl J Med. 2023; 389: 379), misclassification was reduced in the CODE BLUE-J study due to repeated data confirmation. Outcomes were recurrent bleeding within 30 days and 365 days. Exposures were stigmata of recent hemorrhage (SRH) identification and endoscopic treatments. The PAR% was calculated by Levins equation.
[Results] The PAR% of 30-day and 365-day recurrent bleeding due to presumptive CDB, in which SRH were not identified and endoscopic treatments were not performed, were 17.9% and 13.8%, respectively. 42.1% and 27.5% using clipping instead of endoscopic band ligation (EBL); 31.1% and 21.3% by the indirect placement of clips instead of direct deployment.
[Conclusions] The SRH identification and the use of EBL and direct clipping were important to reduce the PAR% of recurrent bleeding.
Index Term 1: colonic diverticular bleeding
Index Term 2: population-attributable risk percent
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